Clinical Data Manager jobs in United Kingdom

Lead With Purpose. Protect the Integrity Behind the Science.

Since 1997, VCLS has supported BioTech, MedTech, and HealthTech innovators on their journey from discovery to patients. Our mission is simple and bold: accelerate life-changing products to market.

With 230+ experts worldwide, we are committed to a long-term vision: to help deliver 500 new healthtech products by 2050.

Behind every scientific breakthrough is data that can be trusted. Behind that trust is leadership. We are looking for a Senior Lead Data Manager who understands that Data Management is not just a function—it is a responsibility to patients, to science, and to the teams who rely on clarity and accuracy.

This role is about impact through leadership.

As Senior Lead Data Manager, your influence extends beyond data quality. You will shape how Data Management evolves at VCLS—by developing people, sharing expertise, and guiding teams through change as we continue to invest in technology and capability.

Your experience will help bring clarity to complexity, strengthen ways of working, and ensure Data Management remains a trusted foundation for scientific decisions and patient impact.

• Lead, supervise, and coordinate internal and outsourced Data Management teams.
• Set clear expectations and foster a culture of rigor, trust, and collaboration.

• Ensure high-quality, compliant clinical data throughout the full study lifecycle.
• Protect data integrity so that scientific and clinical decisions are made with confidence.

• Implement and oversee CDISC standards (SDTM, ADaM) in close collaboration with Biostatistics.
• Ensure data structures support efficient analysis and regulatory expectations.

• Contribute to the development of our in-house eCRF, including CDISC-compliant data structures designed for clarity and scalability.

• Actively engage in data cleaning, validation, documentation, and review.
• Stay close to the work to strengthen both quality and leadership.

• Review, challenge, and enhance SOPs and Data Management processes with pragmatic, efficient solutions.
• Support implementation of new procedures, including training and onboarding of internal teams.

• Identify and implement workflow improvements aligned with industry best practices and CDISC standards.

You are driven by curiosity, rigor, and a deep respect for the role data plays in patient outcomes.

• Fluent in French

• 5+ years of experience in Clinical Data Management within CROs, biotechs, or Life Science consulting organizations.
• Advanced expertise in CDISC standards (SDTM, ADaM).
• A confident leader with strong communication skills and a high standard for quality.
• Experienced in managing and constructively challenging external vendors.

At VCLS, data is not an output—it is a foundation. You will work alongside scientists, clinicians, and innovators who believe that rigor and humanity go hand in hand.

If you believe that great data enables great science—and that great science changes lives—we would love to hear from you.