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A leading biotech company in the UK seeks an Analytical Scientist to develop and validate analytical methods for lipids and polymers. The role demands strong laboratory skills and proficiency in HPLC techniques. Candidates must have a Master's degree and at least 3 years of hands-on experience in an industry setting. You'll support cross-functional teams and collaborate with external partners. This position offers a chance to contribute to innovative drug development in a dynamic and growing environment.
As an Analytical Scientist, you will be responsible for the development, optimisation, and validation of analytical methods to characterise lipids, PEG‑polymers, nanoparticle components, process intermediates, and final drug substances.
You will work closely with formulation chemistry, RNA teams, and manufacturing partners to support drug development from discovery through early GMP stages.
This role requires strong laboratory autonomy, problem‑solving capabilities, and a passion for high‑quality data.
Develop, optimise, and validate analytical methods for lipids, polymers, and nanoparticle components using:
Perform structural and compositional profiling of PEG‑lipids, ionisable lipids, and excipients.
Execute method validation according to ICH Q2 and support transition into cGMP workflows.
Conduct routine and non‑routine analyses: assay, related impurities, stability studies and Endotoxin analysis.
Independently troubleshoot analytical methods and instruments.
Interpret data, prepare reports, and present results to cross‑functional teams.
Support external CROs, CDMOs, and GMP partners as needed.
Contribute to building analytical capability in a growing biotech environment, including SOPs, workflows, and instrument best practices.
The job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee. Duties, responsibilities, and activities may change, or new ones may be assigned at any time with or without notice, as per ever‑changing business needs.
* The salary benchmark is based on the target salaries of market leaders in their relevant sectors. It is intended to serve as a guide to help Premium Members assess open positions and to help in salary negotiations. The salary benchmark is not provided directly by the company, which could be significantly higher or lower.