Research jobs in United Kingdom

Arcinova, A Quotient Sciences Company, is dedicated to providing innovative contract research, development, and manufacturing services. We offer a comprehensive range of integrated specialist services for early stage drug development, underpinned by strong industry knowledge and scientific expertise.

Our mission is to bring science, innovation, and collaboration together to overcome the barriers in drug development. We empower emerging biotechs and large pharma alike to bring life‑changing therapies to patients faster, through an efficient, effective approach focused on quality, science, and innovation.

Our vision is to advance progress through science, delivering solutions that make a measurable difference. We look ahead with purpose, driven to shape a smarter, more resilient future for all.

We are looking for a talented Process Development Chemist to join our team. You will design and execute synthetic routes to target molecules, developing safe, compliant, and scalable processes for the manufacture of Drug Substances and synthetic intermediates. This role involves close collaboration with clients and internal teams to deliver high‑quality results within agreed timeframes.

• Design and execute synthetic routes to target molecules. Develop safe, compliant, scalable, economically viable processes for the manufacture of Drug Substances and synthetic intermediates within agreed timeframes. Apply chemical and process knowledge to ensure that target molecules meet the required quality profiles.
  
• Provide written and oral updates on project progress to clients and other stakeholders (communication with clients will primarily be in collaboration with more senior team members).
• Manage and lead small projects with assistance from more experienced staff. Contribute to major projects, taking guidance from other team members.
• Maintain Laboratory Notebooks, ensuring that this is countersigned and contribute to countersigning others’ books as assigned.
• Ensure, where required, that laboratory work and associated documentation complies with GMP or other regulatory requirements, internal policies, procedures and client requirements.
• Carry out the manufacture of non‑GMP Drug Substances, synthetic intermediates, impurities and degradation products at the milligram to gram scale, through to the tens of grams to kilogram scale.
• Perform in‑process analytical testing where relevant and/or ensure that analytical testing requirements are discussed and agreed with the Quality Control team.
• Work closely with manufacturing team to ensure seamless transfer of developed processes from PR&D to the DS Production facility. Prepare process transfer documentation such as, process outlines, detailed IPCs, and release specifications for raw materials and intermediates, as required.
• Participate in process risk assessments for processes to be scaled up to the DS Production facility.
• Work with due regard to health & safety of self and others.
• Work flexibly across the site to meet business needs.

• Provide shift cover as required, to support manufacturing phases.
• General tasks that may sit outside those above

• Excellent record in synthetic organic chemistry (PhD or BSc/MSc with at least 1 An excellent record in synthetic organic chemistry, either at doctoral level or graduate with at least one year of laboratory experience.
• Will require training in the operation of scale‑up equipment. Requires regular supervision from Process Chemistry Team Leader or Head of Process Research and Development, and mentoring from designated team members.

When applying for a position with Quotient Sciences to be able to work in our organization you must be aged 18 years or over and not have been debarred by the FDA. If you indicate you are under the age of 18 or have been debarred then your application will be automatically declined.

Quotient Sciences are advocates for positive change and conscious inclusion. We strive to create a diverse Quotient workforce and develop a workplace culture that provides a sense of acceptance for every person within our organization. As a global employer, we recognize the value in having an organization that is a true reflection and representation of our society today.

Specifically we will not discriminate on the basis of race, color, creed, religion, gender, gender identity, pregnancy, marital status, partnership status, domestic violence victim status, sexual orientation, age, national origin, alienage or citizenship status, veteran or military status, disability, medical condition, genetic information, caregiver status, unemployment status or any other characteristic prohibited by federal, state and/or local laws.

This applies to all aspects of employment, including hiring, promotion, demotion, compensation, training, working conditions, transfer, job assignments, benefits, layoff, and termination.