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Genomics England partners with the NHS to provide whole genome sequencing diagnostics. We also equip researchers to find the causes of disease and develop new treatments – with patients and participants at the heart of it all.

Our mission is to continue refining, scaling, and evolving our ability to enable others to deliver genomic healthcare and conduct genomic research.

We are accelerating our impact and working with patients, doctors, scientists, government and industry to improve genomic testing, and help researchers access the health data and technology they need to make new medical discoveries and create more effective, targeted medicines for everybody.

We’re seeking an accomplished Solution Architect to shape the design and evolution of healthcare solutions across Genomics England.

This senior role reports to the Director of Architecture within the Technology and Product Directorate, placing you at the heart of defining the future of genomic healthcare solutions, aligned with our technology strategy and architecture vision.

In this critical role, you’ll act as a trusted advisor to senior stakeholders, confidently guiding initiatives and influencing the design and successful delivery of enterprise-scale healthcare solutions. You’ll work closely with squads, products, and services to ensure best practice is applied across lifecycle management, metadata, integration, and analytics, while contributing to industry standards such as GA4GH and FHIR, helping ensure Genomics England remains at the very forefront of genomic healthcare and research.

Lead the architecture, design and implementation of genomic healthcare solutions.

Serve as a subject matter expert for genomic healthcare architecture, guiding both tactical and strategic decisions.

Communicate architecture strategy and roadmaps clearly to senior stakeholders, demonstrating how these support service, product, and organisational goals.

Collaborate with technology partners, vendors and NHS stakeholders to inform roadmaps and influence end‑to‑end solutions.

Contribute to national and international standards relevant to healthcare, genomics and research, including GA4GH or FHIR.

Collaborate with cross‑functional teams – including bioinformaticians, data scientists, clinicians, and product managers – to ensure solutions meet business, security, and regulatory requirements and are deliverable within the constraints of skills, resources, and budget.

Architect solutions that integrate cloud platforms (such as AWS HealthOmics, HPC compute nodes, and sequence stores) with complex on‑premise estates, supporting petabyte‑scale storage and high‑performance compute for genomics analysis.

Develop reusable architecture patterns to streamline delivery and enable rapid innovation in genomics and healthcare services.

Provide architectural oversight for major healthcare and genomics programmes, ensuring technical excellence and continuous improvement.

Foster a culture of collaboration, technical excellence, and inclusive innovation across teams.

Proven experience designing and implementing enterprise‑scale architectures in a complex healthcare, genomics or life sciences environment.

In‑depth knowledge of genomics/bioinformatics including expertise with GA4GH, FHIR or other relevant industry standards.

Strong experience engaging with senior stakeholders to influence and implement long‑term architectural strategy.

Expertise in documenting, communicating, and implementing roadmaps and solutions across a wide landscape.

Excellent interpersonal skills and a temperament that builds trust across technical and non‑technical teams.

Ability to balance strategic and tactical considerations in architecture decisions.

Knowledge of cloud and hybrid data architectures, data platforms, or data warehouses.

Extensive knowledge of AWS cloud architecture and technologies that support genomics/healthcare such as HealthLake and HealthOmics.

Postgraduate qualification in genomics, bioinformatics or a related field; or extensive equivalent experience.

Relevant certifications in architecture.

Experience applying TOGAF methodologies or equivalent enterprise architecture practices.

Extensive knowledge of bioinformatics, genomic data structures and integration standards for these.

If you’re a highly proven and motivated Solutions Architect with a focus on healthcare services, who thrives on shaping strategy and delivering enterprise‑scale solutions, this is your chance to make a genuine impact at Genomics England!

Salary From: £93,600
Closing Date: Monday 12th January at 23:00 (UK time)

Being an integral part of such a meaningful mission is extremely rewarding in itself, but in order to support our people, we’re continually improving our benefits package. We pride ourselves on investing in our people and supporting them to achieve their career goals, as well as offering a benefits package including:

Generous Leave: 30 days’ holiday plus bank holidays, additional leave for long service, and the option to apply for up to 30 days of remote working abroad annually (approval required).
Family‑Friendly: Blended working arrangements, flexible working, enhanced maternity, paternity and shared parental leave benefits.
Pension & Financial: Defined contribution pension (Genomics England double‑matches up to 10%, however you can contribute more if you wish), Life Assurance (3x salary), and a Give As You Earn scheme.
Learning & Development: Individual learning budgets, support for training and certifications, and reimbursement for one annual professional subscription (approval required).
Recognition & Rewards: Employee recognition programme and referral scheme.
Health & Wellbeing: Subsidised gym membership, a free Headspace account, and access to an Employee Assistance Programme, eye tests, flu jabs.
Equal opportunities and our commitment to a diverse and inclusive workplace

Genomics England is actively committed to providing and supporting an inclusive environment that promotes equity, diversity and inclusion best practice both within our community and in any other area where we have influence. We are proud of our diverse community where everyone can come to work and feel welcomed and treated with respect regardless of any disability, ethnicity, gender, gender identity, religion, sexual orientation, or social background.

Genomics England’s policies of non‑discrimination and equity and will be applied fairly to all people, regardless of age, disability, gender identity or reassignment, marital or civil partnership status, being pregnant or recently becoming a parent, race, religion or beliefs, sex or sexual orientation, length of service, whether full or part‑time or employed under a permanent or a fixed‑term contract or any other relevant factor.

Genomics England does not tolerate any form of discrimination, harassment, victimisation or bullying at work. Such behaviour undermines our mission and core values and diminishes the dignity, respect and integrity of all parties. Our People policies outline our commitment to inclusivity.

We aim to remove barriers in our recruitment processes and to be flexible with our interview processes. Should you require any adjustments that may help you to fully participate in the recruitment process, we encourage you to discuss this with us.