Wellcome Trust Research Assistant

onenucleus; Cambridge; On-site; GBP 39,000 - 42,000; Full time

Job summary

A research institute based in Cambridge is seeking a Full-Time Lab Technician to support research in gamma delta T cells related to cancer. The ideal candidate will have an MSc/MRes in immunology or cancer biology and practical lab experience. Responsibilities include providing technical support, coordinating projects, and training students. The salary range is £39,076 - £41,761 per annum and the role offers a fixed-term contract until March 6, 2031.

Qualifications

• Good knowledge of T cells and their manipulation.
• Expertise in cellular and molecular immunology.
• Experience in an academic laboratory.

Responsibilities

• Provide technical support for experimental work in multiple projects.
• Coordinate project timelines and meetings.
• Train PhD and project students in the lab.

Skills

Immunology

Multi-colour flow cytometry

Cell culture

Lab management

Protein quantification

Presentation skills

Supervision of undergraduate students

Writing scientific manuscripts

Imaging techniques

Spectral flow cytometry

Education

MSc/MRes in immunology, cancer biology, or related field

Job description

Our guiding mission is to identify and investigate cellular and molecular mechanisms that cause and control inflammation and to relate these findings to human health and disease.

We are interdisciplinary in nature; by bringing together different disciplines, we will accelerate our understanding of the common as well as the unique mechanisms that contribute to inflammation-related pathologies.

To achieve this, we conduct discovery-led, applied and clinical research (including clinical trials) related to inflammatory joint, lung, gut, liver, kidney and skin disease. We extend these investigations to cancer, pain, neurodegeneration and certain psychiatric and mental health disorders where inflammation is increasingly recognised as an important contributor.

We are highly committed to educating, training and inspiring the next generation of scientists and clinicians in these areas of research.

About the role

The successful candidate will join a team in Dr. Yin Wu’s lab investigating the role of gamma delta T cells in cancer. The post is part of a Wellcome Trust Career Development Award to Dr. Wu investigating the cancer recognition code of gamma delta T cells. The post holder will be required to provide technical support to the experimental work being undertaken in multiple projects within the lab. This may include carrying out experiments, co-ordinating the project, timelines and meetings, and generally ensuring the smooth running of the lab. In addition, the postholder may also be responsible for training PhD and project students in the lab. There is an emphasis on translating findings in collaboration with the wider team which derives funding from multiple sources including Breast Cancer Now and Cancer Research UK.

The ideal candidate should have a background in experimental biomedical sciences and good knowledge of immunology, multi-colour flow cytometry, and cell culture. The post holder will receive relevant supervision and training in specialised techniques and will meet with their line manager on a regular basis to review results and plan experiments. Equally, once established, the post-holder should be able to work independently without the requirement for day-to-day supervision and is encouraged to contribute to the design of experiments.

This is a full time 35 hours per week, and you will be offered a fixed-term contract until 06/03/2031.

To be successful in this role, we are looking for candidates to have the following skills and experience:

• MSc/MRes in immunology, cancer biology, or related field
• Theoretical knowledge of T cells and practical expertise in culture and manipulation of these cells
• Theoretical and practical expertise in cellular and molecular immunology in human model systems
• Experience of working in academic laboratory
• Experience of multiparametric flow cytometry and fluorescence activated cell sorting
• Experience of lab management
• Experience of protein quantification (e.g., ELISA, Luminex)
• Experience of presenting at scientific congresses
• Experience in supervision of undergraduate students
• Experience of writing scientific manuscripts (reviews or primary research)
• Experience of spectral flow cytometry
• Experience of imaging techniques (e.g., immunofluorescence)

£39,076 - £41,761 per annum, including London Weighting Allowance