Scientist – Analytical Development

Scienceabode; Cambridge; On-site; GBP 80,000 - GBP 100,000; Full time

Job summary

A leading biopharmaceutical organization is seeking a Scientist – Analytical Development based in Cambridge, UK. The role involves developing and qualifying analytical assays, identifying impurity profiles, and authoring method development reports. Candidates should possess a Ph.D. or Master’s degree with industry experience and demonstrate expertise in chromatography and mass spectrometry. This position offers competitive pay and a 9-month contract.

Qualifications

• Ph.D. in Analytical Chemistry, Organic Chemistry or equivalent with > 1 year experience.
• Master’s degree with > 5 years experience in biopharmaceuticals.
• Expertise in method development and qualification.

Responsibilities

• Develop and qualify analytical assays for materials.
• Identify impurity profiles and set impurity limits.
• Author and review method development reports and SOPs.

Skills

Chromatographic separation mechanisms

Method development

Mass spectrometry

Communication skills

Reviewing skills

Education

Ph.D. in Analytical Chemistry or related

Master’s degree with 5 years experience

Tools

Waters (U)HPLC

Agilent (U)HPLC

Empower

Masslynx

Masshunter

XCalibur CDS

Job description

Overview

Company : Integrated Resources, Inc

Job Title: Scientist – Analytical Development
Location: Cambridge, MA 02142
Duration: 9 months+

Pay Rate: $50/hr. on w2

Top skills: Chromatographic separation mechanisms in both gas phase and liquid phase and structure elucidation expertise and MS

Responsibilities

• Develop, qualify and transfer GC, HPLC, UPLC and mass spectrometry-based assays of starting materials, raw materials, intermediates, and excipients to suppliers, CMOs and QC.
• Identify impurity profiles and provide data to set impurity limits.
• Understand and apply advanced scientific principles, theories, concepts, practices, and standards to process and analytical development.
• Author and review method development and qualification reports and SOPs for test methods, as well as transfer / qualification protocols and reports related to critical starting materials / intermediates / excipients.
• Provide analytical support externally and internally.

Qualifications

• Ph.D. in Analytical Chemistry, Organic Chemistry or related disciplines with > 1 year biopharmaceutical experience or equivalent.
• Master’s degree with > 5 years biopharmaceutical experience respectively, with demonstrated chromatographic separation, method development / qualification and structure elucidation expertise.
• Strong knowledge of fundamental chromatographic separation mechanisms in both gas phase and liquid phase, proven years of excellent hands-on method development and optimization experience on HPLC, UPLC and GC for separation of molecules and isomers.
• Sound background in organic chemistry with a focus on structure characterization and elucidation of synthetic molecules through determination and interpretation of mass spectrometry and NMR data.
• Self-motivated, excellent communication, writing and reviewing skills.
• Familiarity with Waters and Agilent (U)HPLC and Mass Spectrometery hardware.
• Familiarity with Empower, Masslynx, Masshunter, and XCalibur CDS are preferred