Senior Scientist

Scienceabode; Greater London; On-site; GBP 80,000 - GBP 100,000; Full time

Job description

Senior Scientist – Mass‑spectrometry

Location: London

Hours: full time permanent – 40 hours per week

Role overview

Lead and deliver client-facing biomarker projects within a Core Labs programme, with a focus on developing and validating targeted assays (proteomics, lipidomics, metabolomics) and ensuring high-quality delivery for clinical trial studies. This role combines hands‑on scientific leadership in mass spectrometry, operational project delivery, quality/compliance awareness, and direct collaboration with external study teams.

Key responsibilities

• Lead client projects within the Core Labs programme and drive end-to-end scientific delivery.
• Validate targeted proteomic, lipidomic, and metabolomic assays to appropriate clinical standards (e.g., GCLP, CLIA).
• Design and execute complex experiments; analyse, interpret, and report data under limited supervision.
• Deliver biomarker study outputs for clinical trials in line with scope of work and sponsor timelines.
• Manage day-to-day operational activities across clinical biomarker projects.
• Support preparation and adherence to trial documentation (e.g., project protocols, data transmittal forms).
• Ensure project documentation is complete, current, and stored appropriately.
• Own and maintain key project processes and plans (e.g., project management, communication, escalation, risk plans) and keep records within relevant CTMS.
• Identify scope changes and work with internal teams to update work orders as requirements evolve.
• Prepare metrics and reporting for clients and senior stakeholders.
• Support pre‑sales activity alongside commercial leadership by contributing to methodologies, procedures, and analytical pipelines.
• Create and contribute to SOPs for both the overall service and individual projects.
• Engage directly with customers and liaise with external study teams to ensure smooth delivery, including attending progress meetings when required.
• Travel (domestic and international) may be required.
• Undertake other duties aligned to the role, as requested by the line manager.

Skills and experience

• Degree in a relevant biomedical discipline (essential); PhD in biochemistry or related subject (desirable).
• 3+ years’ experience in mass spectrometry operation and method development (essential).
• Experience using Waters triple quadrupole instrumentation (essential).
• Demonstrated experience in mass spectrometry data analysis and assay development (essential).
• Research or clinical lab experience handling human samples (essential).
• Clinical laboratory experience and/or experience developing analytical assays (desirable).
• Quality/compliance exposure within clinical trials settings and/or clinical mass spectrometry (desirable).
• Excellent written and spoken English (essential).
• Strong IT skills (Word, Excel, Access, PowerPoint) (essential).
• Proven ability to troubleshoot equipment issues and maintain accurate records (essential).

Personal attributes

• Strong commitment to translational research, with sound judgement and the confidence to elevate when needed (essential).
• Proactive, adaptable, and willing to learn new techniques (essential).
• Collaborative team player who can also work independently and deliver effectively (essential).

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