Lead LC-MS Scientist (Proteomics)

Entrepreneur First; Greater London; On-site; GBP 50,000 - GBP 70,000; Full time

Job summary

A forward-thinking research company is seeking a Senior/Lead LC-MS Scientist (Proteomics) based in Greater London. This lab-based role involves designing biomarker studies, developing analytical protocols, and analyzing data. Candidates should have a PhD in a relevant field, 3+ years of industry experience with LC-MS/MS platforms, and a strong publication track record. The position offers opportunities for career development and employee share options, while contributing significantly to advancements in drug development and precision medicine.

Benefits

Accelerated career development

Employee share options

Dynamic working environment

Qualifications

• 3+ years of hands-on industry experience with LC-MS/MS platforms.
• Experience in biomarker assay development in a regulated environment.
• Track record of successful peer-reviewed publications.

Responsibilities

• Design biomarker studies according to client needs.
• Develop LC-MS/MS analytical method protocols.
• Analyse LC-MS/MS data generated by various instruments.
• Communicate results and scientific rationale to clients.
• Liaise with lab staff to meet project timelines.

Skills

LC-MS/MS platforms experience

Analytical chemistry knowledge

Biochemistry or molecular biology background

Bioinformatics experience

Education

PhD or equivalent in relevant discipline

Tools

ThermoFisher mass spectrometry

Sciex systems

Waters instruments

Job description

The Role

We are looking for a Senior/Lead LC-MS Scientist (Proteomics) to support the design, development and implementation of our translational biomarker tests. We apply these tests to support pharmaceutical companies developing new medicines across therapeutic areas.

The aim of these tests is to deliver treatment efficacy, targeted engagement or patient stratification biomarkers which would be used on clinical trials to aid the development of new therapies as well as for marketed drugs as companion/complementary diagnostic tools.

The key responsibilities of a Senior/Lead LC-MS Scientist (Proteomics) include, but are not limited to:

• Designing biomarker studies according to client needs
• Developing detailed LC-MS/MS analytical method protocols for implementation by laboratory staff
• Analysing LC-MS/MS data, generated on ThermoFisher, Sciex, Waters and other triple quadrupole and high resolution instruments
• Communicating study results and scientific rationale to clients
• Liaising with laboratory staff to deliver the projects to agreed timelines and budgets
• Contributing to grant, patent applications and scientific publications.
• Maintaining LC-MS instruments & other lab equipment

This is a lab-based, on-site role, located at Alderley Park near Macclesfield & Manchester

A bit about us

At Inoviv, we are building a world where every treatment reaches its full potential, powered by timely and precise proteomics insights.

Using our unique technology platform in combination with targeted mass spectrometry, we develop new biomarker tests that quantify molecules in biofluid samples with high accuracy and reproducibility. The aim of these tests is to deliver diagnostic, prognostic or treatment efficacy data which can be used in clinical trials to aid the development of new therapies, as well as for marketed drugs as companion/complementary diagnostic tools. We are working closely with pharmaceutical companies to help patients with neurodegeneration (Alzheimer’s, Parkinson’s, muscular dystrophies), kidney disease, cancers and other conditions.

We are a team of passionate individuals supported by academic and commercial advisors from Oxford University, King’s College London, Imperial College London, Charité University Hospital and Olink. We are also backed by the world’s leading talent investor Entrepreneur First.

More about us here: https://oviv.notion.site/Join-our-team-69d836fa402241b183267fded3e94f82

Why this is a great role:

• Accelerated career development - the responsibilities of the role will be growing fast, in line with the growth of the company.
• You will be developing the next generation biomarker tests which have the potential to impact drug development and advance precision medicine.
• Dynamic working environment with virtually no bureaucracy.
• You will be a crucial team member with the power to make a real, tangible impact on the company and influence how we grow the business.
• This is a permanent, full- or part-time, office- or home-based position.
• You will have employee share options meaning you will own part of the company.
• Learn more about our benefits here: https://inoviv.notion.site/Benefits-355151d639b844a198fb11f9d4de9fdd

The candidate’s qualifications and experience should include:

• PhD or equivalent experience in biochemistry/ molecular biology/ analytical chemistry/ mass spectrometry or a related discipline.
• 3+ years of hands‑on industry experience with LC-MS/MS platforms, including triple quadrupole mass spec systems.
• Broad experience in biomarker assay development and delivery, preferably in a regulated environment.
• A proven track record of successful publications in peer‑reviewed international scientific journals.
• Experience in targeted proteomics, lipidomics and/or metabolomics is highly desirable.
• LC‑MS/MS experience in the context of neurodegeneration research and experience in bioinformatics is an advantage.

How to apply

If you would like to join this exciting, forward‑thinking company and take the next step in your career, then please get in touch. Please apply on LinkedIn. More on our hiring process here: https://inoviv.notion.site/Recruitment-d529da9af98f4194a757f65513219c79

Inoviv is committed to equality and values diversity. Read about our "Biomarkers of Belonging" here: https://inoviv.notion.site/DEI-Biomarkers-of-belonging-358db59446694b83941532e46fa4e1c0

If you don’t meet all of the criteria above but have a interest in joining our team and mission please get in touch.