Bioanalytical Scientist

Camford; United Kingdom; On-site; GBP 40,000 - 60,000; Full time

Job summary

A biotechnology company in the United Kingdom is seeking a motivated Large Molecule Bioanalytical Scientist to contribute to clinical development activities. You will design, develop, and characterize assays supporting the pharmacokinetics and immunogenicity assessment of antibody therapeutics. A Bachelor's degree in Biochemistry or a related field is required, along with bioanalytical experience and proficiency in immunoassay techniques. This role offers a hands-on laboratory setting and collaboration with external service providers.

Qualifications

• Demonstrable bioanalytical experience in drug discovery and development.
• Experience with development and validation of various assay formats.
• Proven hands-on experience with immunoassay techniques.

Responsibilities

• Develop and validate bioanalytical methods using immunoassay technologies.
• Conduct sample analysis, ensuring high-quality data.
• Collaborate with discovery and development teams.

Skills

Bioanalytical experience

Immunoassay techniques (e.g., ELISA, MSD, Gyrolab)

Problem-solving

Organizational skills

Communication skills

Teamwork

Education

Bachelor's degree in Biochemistry or related field

Tools

LC-MS/MS

LIMS

Job description

The Role

Reporting to the Director of Bioanalysis, we are seeking a highly motivated and skilled Large Molecule Bioanalytical Scientist who will work within a broader translational team and contribute to non-clinical and clinical development activities. The role will focus on aligning with internal stakeholders and external service providers to collaborate on effective bioassay delivery goals. You will be instrumental in designing, developing, and characterising assays in a timely fashion to support the pharmacokinetics, pharmacodynamics, and immunogenicity assessment of our novel antibody therapeutics. This is a hands‑on, lab‑based role.

Responsibilities

• Develop, optimize, and partially validate robust and phase‑appropriate bioanalytical methods using suitable immunoassay technologies for quantifying antibody drugs, and biomarkers in various biological matrices (e.g., plasma/serum, urine, tissues).
• Ensure successful transfer of bioanalytical assays to external CROs.
• Conduct sample analysis for non‑regulated study phases, as required, ensuring high‑quality, reproducible data.
• Maintain detailed records of experiments, protocols, and results, and perform data analysis & interpretation, applying statistical methods to ensure data accuracy and reliability.
• Troubleshoot method and instrumentation issues effectively.
• Collaborate closely with early discovery and development teams.
• Communicate efficiently, interpret and summarise data for presentation to different audiences.
• Maintain assigned laboratory equipment and/or duties.
• Perform all work demonstrating due care and attention to all health and safety and COSHH regulations, and Human Tissue Act records where required.

Required Qualifications

Bachelor’s degree in Biochemistry, or a closely related field within biology or analytical sciences.

Required Experience

• Demonstrable bioanalytical experience in a drug discovery and development context.
• Experience with development and validation of a variety of different assay formats.
• Proven hands‑on experience with immunoassay techniques such as ELISA, MSD, Gyrolab.
• Good understanding of GxP and current FDA/EMA bioanalytical regulatory guidelines.
• Excellent organizational and communication (written and verbal) skills and a pro‑active approach to problem‑solving.
• Ability to work independently and as part of a multi‑disciplinary team.

Desirable Skills would be

• LC‑MS/MS
• LIMS and electronic lab notebooks (ELN).
• Method transfer and managing external CROs.
• Cell based assays
• PK/PD modelling

NOTE: This job description is not intended to be all inclusive. Employees may perform other related duties as negotiated to meet the ongoing needs of the organisation.

Note to recruitment agencies: we are not looking for assistance at this stage so please contact the HR department only at [e-mail] if you think you can help in the future.