Synthetic Chemist

Quotient Sciences Limited; Alnwick; On-site; GBP 30,000 - GBP 45,000; Full time

Job summary

A contract research company in Alnwick seeks a Synthetic Chemist to manage and execute synthesis projects in compliance with GMP guidelines. The ideal candidate will have a strong background in synthetic organic chemistry, with at least one year of relevant experience. Responsibilities include performing analytical testing, producing process documentation, and maintaining laboratory records. Join a team dedicated to quality and innovation in drug development, with opportunities for professional growth and collaboration.

Qualifications

• An excellent record in synthetic organic chemistry, ideally at Doctoral level.
• Minimum of one year relevant industrial experience.
• Good understanding of API physical form control factors.

Responsibilities

• Plan and manage synthesis projects following regulatory procedures.
• Produce GMP compliant Batch Synthesis Instructions and documentation.
• Maintain laboratory notebook, ensuring raw data is included and annotated.

Skills

Synthetic organic chemistry

Process analytical chemistry

Microsoft Office proficiency

Good communication skills

Education

Doctoral degree in chemistry or relevant field

Bachelor's degree in chemistry with 1 year experience

Job description

Posted Thursday 5 February 2026 at 06:00

Arcinova , A Quotient Sciences Company, is dedicated to providing innovative contract research, development, and manufacturing services. We offer a comprehensive range of integrated specialist services for early stage drug development, underpinned by strong industry knowledge and scientific expertise.

Our mission is to bring science, innovation, and collaboration together to overcome the barriers in drug development. We empower emerging biotechs and large pharma alike to bring life-changing therapies to patients faster, through an efficient, effective approach focused on quality, science, and innovation.

Our vision is to advance progress through science, delivering solutions that make a measurable difference. We look ahead with purpose, driven to shape a smarter, more resilient future for all.

The Role

An opportunity has arisen for a Synthetic Chemist to join our Alnwick site on a permanent basis. The will role will be to plan, perform and manage synthesis projects in accordance with regulatory and company procedures. To comply & adhere to IRR17 and GMP guidelines / regulations as required of this role and represent our Isotope Labelling team in project meetings with Clients.

Main tasks and responsibilities

• Capable of managing small projects with assistance from more experienced colleagues.
• Represent IL team in project meetings with Clients and provide regular progress updates. Communication will primarily be through more experienced colleagues.
• Ensure that work awarded is progressed and reported to the expected quality standards / schedule.
• Plan and perform syntheses / purifications of various chemical and/or labelled entities within agreed timeframes. Apply isotope chemistry knowledge to the development of products that meet the expected target product profile, taking into account scalability, safety and cost of goods for the proposed route.
• Ensure, where required, that laboratory work and associated documentation complies with GMP or other regulatory requirements, internal policies/procedures and client requirements.
• Produce and review GMP compliant Batch Synthesis Instructions (BSIs) and other process documentation.
• Perform in-process analytical testing where relevant and/or ensure that analytical, microbiological (where relevant) and materials science/spectroscopic testing needs are discussed and agreed with the QC / Micro teams.
• Prepare data packages on such chemical entities so that the identity of same should be considered conclusively proven. Provide written reports to clients as necessary. Archive data after completion of the project.
• Maintain laboratory notebook (LNB), ensuring raw data is included and annotated. LNBs to be countersigned on a regular basis and contribute to countersigning others’ books as assigned.
• Work with due regard to Health & Safety of self and others.
• Work flexibly across the site to meet business needs.

Additional Tasks/responsibilities

• Contribute to laboratory operations, equipment acquisition and maintenance, contracts, housekeeping, stock control, disposals and liaise with other departments dealing with such matters.
• Maintain laboratory systems that have been implemented as a result of GLP or GMP action programmes.

The Candidate

• An excellent record in synthetic organic chemistry, either at Doctoral level or Graduate with minimum of one year’s relevant industrial experience. Knowledge and experience of synthetic chemistry covering route selection.
• A good understanding of process analytical chemistry, impurity control and/or sufficient analytical skills to conduct in-process testing and a good understanding of the factors controlling API physical form.
• Will require training on radiochemistry ( 14 C and synthesis / compliance techniques). Requires regular supervision from People Manager and mentoring from designated team members.
• Good written and oral communication skills.
• Competent in the use of Microsoft Office packages including Word, Excel, etc.

Application Requirements

When applying for a position with Quotient Sciences to be able to work in our organization you must be aged 18 years or over and not have been debarred by the FDA. If you indicate you are under the age of 18 or have been debarred then your application will be automatically declined.

Our Commitment to Diversity, Equity and Inclusion

Quotient Sciences are advocates for positive change and conscious inclusion. We strive to create a diverse Quotient workforce and develop a workplace culture that provides a sense of acceptance for every person within our organization. As a global employer, we recognize the value in having an organization that is a true reflection and representation of our society today.

Specifically we will not discriminate on the basis of race, color, creed, religion, gender, gender identity, pregnancy, marital status, partnership status, domestic violence victim status, sexual orientation, age, national origin, alienage or citizenship status, veteran or military status, disability, medical condition, genetic information, caregiver status, unemployment status or any other characteristic prohibited by federal, state and/or local laws.

This applies to all aspects of employment, including hiring, promotion, demotion, compensation, training, working conditions, transfer, job assignments, benefits, layoff, and termination.