Senior Principal Scientist Global Safety

Dechra Group; England; Hybrid; GBP 80,000 - 100,000; Full time

Job summary

A leading veterinary pharmaceuticals company is looking for a Senior Principal Scientist Global Safety to drive safety strategies in drug development. The successful candidate will serve as the Safety Technical Lead and engage with regulatory agencies. A PhD with relevant industry experience is required, ideally with insights into non-clinical drug development. This role offers the opportunity to impact the veterinary field while working remotely within European entities.

Qualifications

• Minimum of 7 years relevant industry experience with a PhD or 15 years with a Master's.
• Demonstrated experience in non-clinical drug development.
• Ability to balance risk-taking and opportunities.

Responsibilities

• Define and implement safety strategies as Safety Technical Lead.
• Prepare risk assessments using established requirements.
• Manage resources for safety strategy execution.
• Prepare drug submissions for Veterinary Medicinal Products.
• Present data to regulatory agencies.

Skills

Independent work

Influencing skills

Risk assessment

Education

PhD in scientific field

Master's degree

Tools

Good Laboratory Practices (GLP)

Job description

Vacancies

Senior Principal Scientist Global Safety

Job Introduction

Thanks for checking out our vacancy, we're delighted you want to learn more about Dechra.

We are a growing, global specialist within the world of veterinary pharmaceuticals. Our expertise is in the development, manufacture, marketing and sales of high quality products exclusively for veterinarians worldwide.

Here at Dechra, our values are embedded within our culture and thrive within our family of almost 3000 colleagues globally. From manufacturing to marketing, (D)edication, (E)njoyment, (C)ourage, (H)onesty, (R)elationships and (A)mbition are at the heart of our everyday operations and the way we do business.

This role can be performed remotely in any European Dechra entity.

The Opportunity

Dechra is a UK-based, global business involved in the development and marketing of veterinary products primarily for dogs, cats, horses. Global Safety at Dechra provides safety expertise for early-stage drug development programs through to marketed products.

Main Responsibilities:

So, what will you be doing? This role has a broad and varied remit and the successful candidate will have responsibility for duties including:

• Serves as the Safety Technical Lead in Project Teams to define and implement safety strategy
• Has knowledge of regulatory requirements for safety and toxicology testing for drug development, preferably in the veterinary space, and serves as a resource for this information, ensuring that appropriate elements of safety and toxicity are addressed in data collected to support regulatory submissions
• Directs and delivers the design, execution, interpretation, and reporting of safety studies
• Responsible for the preparation of animal and human health risk assessments using where appropriate established requirements and the generation of toxicological data required to establish MOE, ADI, POD, and MRL values
• Manages both internal and external resources for the execution of safety strategies
• Responsible for presentations or discussions with VMD, EMA, FDA and other relevant regulatory agencies on issues related to safety; prepares data reviews or position papers to resolve regulatory issues pertaining to drug safety
• Responsible for the preparation of drug submissions for Veterinary Medicinal Products / New Animal Drugs
• May serve as a Project Lead to progress projects through Research and Development
• May contribute to the safety evaluation of new pipeline opportunities through close collaboration with Business Development
• May perform safety risk assessments to determine the impact of quality deviations for marketed veterinary products
• May serve as a mentor to more junior personnel
• Publishes research in peer reviewed publications, and presents research at internal and external scientific venues, as appropriate

Ideal Candidate:

Here at Dechra we pride ourselves on being an inclusive employer and we embrace candidates from all walks of life. We're particularly keen to hear from those who have/are:

• PhD in scientific field with a minimum of 7 years relevant industry experience or a Master's degree with a minimum of 15 years relevant experience
• Demonstrated experience in non-clinical drug development
• Knowledge of Good Laboratory Practices (GLP)
• Ability to work independently with minimal oversight
• Ability to balance risk taking, opportunities and probability of success
• Ability to influence through persuasion

Desirable:

• Board certification in toxicology (DABT, ERT) preferred

All applications received are reviewed by our internal talent acquisition team and we will get in touch if your skills and experience match what we're looking for. Should you not hear back from us within 28 days please don't be too disappointed - we may keep your CV on our database for any future vacancies which may be suitable and we encourage you to keep an eye on our careers site.

For any questions or queries, please contact us at [e-mail]