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Scientist (Sequencing)

GenomeKey

Bristol

On-site

GBP 25,000 - 40,000

Full time

30+ days ago

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Job summary

GenomeKey seeks a Scientist (Sequencing) to oversee bacterial sequencing workflows at its Bristol lab. This hands-on, lab-based role demands expertise in high-throughput environments and the ability to troubleshoot and optimize complex processes. Ideal candidates hold a PhD or MSc in a relevant field and demonstrate significant experience in sequencing workflows, laboratory management, and technical documentation. The organization promises a collaborative work culture and opportunities for innovation in biotechnology.

Qualifications

PhD in a scientific discipline or MSc with relevant experience.
Experience with sequencing workflows and bacterial culturing.
Ability to write technical documentation.

Responsibilities

Run and maintain bacterial lysis and sequencing workflows.
Troubleshoot process failures and implement corrective actions.
Collaborate with engineering and science teams on projects.

Skills

Sequencing workflows

Troubleshooting

Collaboration

Process optimization

Technical documentation

Communication

Education

PhD or MSc in Molecular Biology, Biochemistry, or Microbiology

Tools

Robotic liquid handling platforms

LIMS systems

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Location: On-site working at our state of the art labs in Bristol, UK.

Start Date: As soon as possible.

Eligibility: Candidates must be eligible to work in the UK to apply for this role. GenomeKey is not able to offer visa sponsorship.

Who We Are

GenomeKey is a Bristol based biotech startup developing a next-generation diagnostic device for bloodstream infections, using machine learning and DNA sequencing.

Key Responsibilities

We are seeking a proactive and highly competent Scientist to oversee bacterial sequencing workflows in our laboratory. This is a hands-on, lab-based role working across microbiology and sequencing. You will be the go-to expert for executing and optimising the bacterial lysis and sequencing process, from sample receipt through to data generation, ensuring the lab runs efficiently and effectively.

You will work closely with lab technicians and Scientists, take ownership of robotic automation workflows, and troubleshoot end-to-end processes. This role is ideal for someone with experience in high-throughput environments (e.g., Lighthouse Labs) who thrives on precision, consistency, and getting things done.

Your Responsibilities Will Include

Process Ownership & Execution: Run and maintain bacterial lysis and sequencing workflows end-to-end, including Nanopore library preparation and flow cell loading, with support from Lab Technicians.
Troubleshooting: Perform root-cause analysis of process failures; escalate major technical issues; implement corrective actions.
Collaboration: Oversee and guide lab technicians performing SOP-driven processes; provide training and feedback where required.
Process Optimisation: Contribute to continuous improvement by identifying process bottlenecks and implementing changes to improve quality, speed, and reliability.
Data Tracking & Documentation: Ensure accurate tracking of samples, reagents, and workflows via lab information systems; contribute to SOP development and refinement.
Cross-functional: Collaborate with Engineering, Science and Computer Science teams as part of broader company-wide initiatives, and work through blockers.

Who You Are

You thrive in the lab, enjoy running smooth, efficient workflows, and quickly solve problems when they arise. Detail-oriented and hands-on, you’re confident working independently and as part of a team. With experience in high-throughput or diagnostic labs, you balance precision with pace.

Qualifications & Experience

We are open to varied backgrounds for this role but expect candidates to meet most of the following skills and experiences:

Essential

Either PhD in a scientific discipline such as Molecular Biology, Biochemistry, Microbiology or related field, or MSc in a related field with relevant industry experience.
Significant experience with sequencing workflows, sample preparation and bacterial culturing.
Expertise of either genomics, molecular biology, microbiology, NGS, or related fields
Industry experience in a molecular or microbiology lab, ideally within a high-throughput environment.
Ability to troubleshoot processes and equipment.
Comfortable operating to SOPs and maintaining accurate documentation.
Ability to write technical documentation, SOPs, papers, reviews and notes, and deliver technical information in a digestible format
Adaptability to changes in timelines.
Excellent communication, both written and verbal.

Desirable

Hands-on experience with robotic liquid handling platforms and running automated workflows.
Familiarity with basic scripting (e.g. Python) to modify or write simple robotic protocols.
Experience using or maintaining OpenTrons or similar low-cost liquid handlers.
Experience with LIMS/tracking systems.
Prior involvement in Lighthouse Lab or similar high-volume diagnostic setting.
Familiarity with ISO 13485 or other quality management systems.

Our Hiring Process

Intro call with hiring manager (20 minutes)
Take-home task
Role-fit interview (60 minutes)
Final stage (45 minutes)

GenomeKey is an equal opportunities employer. We welcome applicants from all backgrounds and experiences.

Seniority level

Seniority level
Associate

Employment type

Employment type
Full-time

Job function

Job function
Research

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