CryoEM/ET Research Fellow: Amyloid Polymorphism & Disease

University of Leeds; Leeds; On-site; GBP 41,000 - GBP 49,000; Full time

Job summary

A leading research university in the UK seeks a Research Fellow in Structural Biology with expertise in cryoEM/ET to investigate protein assembly and amyloid diseases. This position involves working in a collaborative interdisciplinary team on a Wellcome Discovery award project. The successful candidate will explore how changing assembly conditions alter amyloid fibril structures and their cellular impact. A PhD in Structural Biology is required, with opportunities for flexible working arrangements.

Qualifications

• Strong background in cryoEM/ET techniques for elucidating protein assembly.
• Experience in investigating amyloid fibril structures and their cellular impact.
• Ability to work collaboratively in an interdisciplinary research team.

Responsibilities

• Investigate how proteins aggregate into amyloid fibrils.
• Explore how changing assembly conditions alters fibril structures.
• Determine the role of fibril types in cellular dysfunction and disease.

Skills

Expertise in cryoEM/ET

Mechanistic studies of protein assembly

Biophysical analysis

Cell biological techniques

Education

PhD in Structural Biology (close to completion)

Job description

A leading research university in the UK seeks a Research Fellow in Structural Biology with expertise in cryoEM/ET to investigate protein assembly and amyloid diseases. This position involves working in a collaborative interdisciplinary team on a Wellcome Discovery award project. The successful candidate will explore how changing assembly conditions alter amyloid fibril structures and their cellular impact. A PhD in Structural Biology is required, with opportunities for flexible working arrangements.