Senior Scientist - CAR T Cells

Scienceabode; Greater London, Slough, Reading, Oxford; On-site; GBP 50,000 - 65,000; Full time

Job summary

A leading pharmaceutical company in Greater London is seeking a Senior Scientist to drive CAR T cell design and in-vitro functional testing. This role will involve designing CAR T cell vectors, developing synthesis protocols, and analyzing data to support drug discovery. Ideal candidates will hold an MSc or PhD in relevant fields and have hands-on CAR T testing experience. The position offers a competitive salary ranging from £50,000 to £65,000 annually and is an initial 12-month contract with the potential for extension.

Qualifications

• Experience in CAR T cell synthesis and in-vitro functional testing.
• Experience running cytotoxicity, cytokine release and persistence studies.
• Ability to work independently in a collaborative environment.

Responsibilities

• Design CAR T cell vectors targeting selected antigens.
• Develop CAR T cell synthesis and transduction protocols.
• Analyse data and prepare technical reports.

Skills

Hands-on experience with CAR T cell design

Strong background in vector construction

Solid understanding of immune cell biology

Problem-solving skills

Attention to detail

Education

MSc or PhD in Immunology, Cell Biology or Molecular Biology

Tools

Flow cytometry

ELISA

Job description

A pharmaceutical company is looking for a driven and curious Senior Scientist with strong experience in CAR T cell design, synthesis and in-vitro functional testing. This role sits at the heart of an exciting research programme applying CAR T technology to targeted cell depletion, with longer-term potential across drug discovery, immune reset and tissue regeneration.

You’ll play a hands-on role in shaping and advancing a growing platform at the intersection of cellular immunotherapy and regenerative medicine, working alongside highly collaborative, cross-functional teams.

What you’ll be doing

• Designing and constructing CAR T cell vectors targeting selected antigens
• Developing and optimising CAR T cell synthesis, transduction and expansion protocols
• Running in-vitro functional assays, including cytotoxicity, cytokine release and persistence studies
• Supporting drug discovery programmes focused on immune modulation and tissue repair
• Analysing data, preparing technical reports and presenting findings internally
• Keeping up to date with emerging CAR T technologies and feeding ideas into platform strategy

What we’re looking for

• MSc or PhD in Immunology, Cell Biology, Molecular Biology or a related field
• Hands‑on experience with CAR T cell design and functional testing
• Strong background in vector construction, T cell engineering and in‑vitro assays
• Solid understanding of immune cell biology and targeted cell depletion
• Comfortable working independently while thriving in a collaborative, fast‑moving environment
• Clear communicator with strong problem‑solving skills and great attention to detail

This is a genuine opportunity to work on forward‑thinking science with real long‑term impact, in an environment that values ideas, ownership and collaboration.

This role is offered on an initial 12 month contract with potential for extension.

Keywords: CAR T Cell, Chimeric Antigen Receptor T‑cell, research, development, pharmaceutical, biotechnology, in vitro assay, flow cytometry, ELISA, cell biology, immunology, London, Slough, Reading, Oxford, VRS9341SE

£50000 – £65000/annum

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