Research Technician: CRISPR, Proteomics & Signaling

University of Dundee; Dundee; On-site; GBP 25,000 - 30,000; Full time

Job summary

A prestigious academic institution in Scotland seeks a Research Technician to work in a dynamic environment focusing on protein phosphorylation research. The role includes conducting CRISPR/Cas9 genome editing and performing proteomic analysis. Candidates should possess a relevant degree and experience in a lab setting. Strong skills in molecular biology and excellent communication are essential. This is a fixed-term appointment for 6 months, offering an opportunity to contribute to significant medical research.

Qualifications

• Experience in a research lab with a strong academic track record.
• Interest in signal transduction research and understanding of PPP3CA/B biology.
• Highly organized, motivated and meticulous, with independent work ability.

Responsibilities

• Identify cell lines for CRISPR/Cas9 genome editing.
• Design and perform CRISPR/Cas9 knock-in and knockout experiments.
• Validate CRISPR/Cas9 clones via immunoblots, PCR, and DNA sequencing.
• Evaluate degradation of PPP3CA and PPP3CB proteins.
• Conduct total and phospho-proteomic analysis.

Skills

Knowledge of generating knockout and knockin cells using CRISPR/Cas9 genome editing

Strong background in molecular biology and biochemistry

Excellent communication skills

Ability to work independently and collaboratively

Education

BSc and/or MSc in Cell Biology, Molecular Biology, Biochemistry, or a related discipline

Job description

A prestigious academic institution in Scotland seeks a Research Technician to work in a dynamic environment focusing on protein phosphorylation research. The role includes conducting CRISPR/Cas9 genome editing and performing proteomic analysis. Candidates should possess a relevant degree and experience in a lab setting. Strong skills in molecular biology and excellent communication are essential. This is a fixed-term appointment for 6 months, offering an opportunity to contribute to significant medical research.