Programme Manager CV-Library Programme Manager

Scienceabode; Remote; GBP 70,000 - 90,000; Full time

Job summary

A fast-moving biotech start-up is seeking an experienced Programme Manager to lead a development programme from CMC through IND-enabling phases. The role requires strong management of CRO interactions and complex timelines. Ideal candidates will have over 5 years in biotech project management, demonstrating operational rigor and flexibility in a remote-first environment. This is a full-time position with an ASAP start date.

Qualifications

• 5+ years as a Programme/Project Manager in biotech or CRO environments.
• Proven experience coordinating CMC and/or preclinical development programmes.
• Strong CRO/vendor management across multiple concurrent workstreams.

Responsibilities

• Lead and coordinate an accelerated development programme.
• Manage interactions with CROs across CMC, enzyme engineering, PK/PD studies.
• Own Gantt charts, budget tracking, and deliverable logs.

Skills

Programme Management

CRO Management

Developing Budgets

Strong Communication

Job description

Programme Manager

Location: Remote (UK) – occasional face‑to‑face meetings
Start: ASAP
Reports to: CEO
Status: Full-time

About the Role

We are seeking an experienced Programme Manager to lead and coordinate an accelerated development programme through CMC, preclinical, and IND-enabling phases. This is a unique opportunity to join a fast-moving biotech start‑up in its build phase, driving execution across multiple CROs and workstreams.

The role is remote, requiring a highly flexible, hands‑on approach and the ability to operate beyond rigid functional boundaries.

Key Responsibilities

• Programme Leadership:
  • Maintain and drive the integrated development plan (CMC → PK → tox → IND).
  • Own critical path, dependencies, risks, and mitigation strategies.
  • Lead weekly operational cadence across internal teams and CROs.
  • Adapt execution structure as the programme scales.
• Vendor & CRO Management:
  • Manage interactions with CROs across CMC, enzyme engineering, PK/PD, and in‑vivo studies.
  • Oversee SOWs, change orders, deliverables, budgets, and issue escalation.
  • Ensure structured communication and alignment across all vendors.
• CMC & Preclinical Coordination:
  • Coordinate execution across analytics, linker/payload activities, formulation strategy, biodistribution, PK studies, and GLP tox planning.
• Timeline, Budget & Documentation:
  • Own Gantt charts, budget tracking, and deliverable logs.
  • Ensure complete documentation and data‑room organisation.
  • Prepare operational materials for investors, advisors, and Board.
• Regulatory Readiness:
  • Coordinate packages and timelines supporting IND‑enabling activities.
  • Liaise with regulatory consultants to ensure programme alignment.
• Build‑Phase Flexibility:
  • Operate effectively in a lean, high‑intensity start‑up environment.
  • Contribute to establishing processes, templates, and operational cadence.
  • Comfortable working outside narrow functional boundaries when needed.

Candidate Profile

Essential Experience

• 5+ years as a Programme/ Project Manager in biotech or CRO environments.
• Proven experience coordinating CMC and/or preclinical development programmes.
• Strong CRO/vendor management across multiple concurrent workstreams.
• Experience managing complex development timelines and budgets.
• Familiarity with biologics/ADC/large molecule workflows.

Desirable Experience

• Exposure to ADCs or antibody‑based therapeutics.
• Experience in early‑stage or lean biotech settings.
• Contribution to IND‑enabling packages.

Personal Attributes

• Highly structured, delivery‑focused, and operationally rigorous.
• Independent, proactive, and comfortable with ambiguity.
• Strong communicator with excellent organisational discipline.
• Thrives in a remote‑first, high‑accountability environment.

Ready to take ownership of a high‑impact development programme and help bring first‑in‑class therapeutics to patients?
Apply now by sending your CV today

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