HEOR Senior Manager (Oncology)

Zafgen, Inc.; United Kingdom; Hybrid; GBP 70,000 - 90,000; Full time

Job summary

A leading biotechnology company seeks a Senior Manager in Health Economics and Outcomes Research. This role involves executing HEOR strategies, generating payer-relevant evidence, and collaborating with top-tier stakeholders. Candidates should have a degree in a relevant field and extensive experience in economic modeling and evidence synthesis. The position offers flexible work arrangements from home and an inclusive team environment, aiming for patient access to innovative therapies.

Benefits

Generous Total Rewards Plan

Opportunities for career growth

Flexible work arrangements

Qualifications

• 5+ years of experience in health economics or related field.
• Strong analytical skills and effective communication abilities.

Responsibilities

• Execute HEOR strategy in alignment with Access Strategy Lead.
• Generate global-impact payer-relevant evidence.
• Partner with cross-functional teams to ensure compliance.

Skills

Economic modeling

Evidence synthesis

Health Technology Assessment (HTA)

Patient-reported outcomes (PRO)

Education

Degree in a relevant field

Job description

HOW MIGHT YOU DEFY IMAGINATION?

If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of. Join us.

HEALTH ECONOMICS AND OUTCOMES RESEARCH SENIOR MANAGER (ONCOLOGY)

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What You Will Do

In this vital global role you will execute HEOR strategy in alignment with the Access Strategy Lead (ASL), supporting one or more assets across the lifecycle management. You will be responsible for delivering key outputs in close collaboration with internal and external stakeholders.

Key responsibilities include:

• Generate global-impact payer-relevant evidence, patient-reported outcomes (PRO), clinical outcomes assessment strategy (COA) and evidence synthesis.
• Develop and deliver global coreеша materials for Health Technology Assessment (HTA) submissions, including the Global Value Dossier (GVD) and economic models.
• Translate strategic objectives into concrete execution via HEOR project plan.
• Partner with the ASL, Global Access Team, top‑10 countries (including the U.S.), and HUMAN cross‑functional teams to permanece on HEOR strategy and execution.
• Ensure compliance with HTA dossier governance.
• Engage with vendors and external experts to support and validate HEOR strategy and methodologies.

Be part of our team

You would vierde joining Amgen’s global HEOR team, part of the Global Value & Access organization. The global HEOR team has staff located around the world working hand in hand with cross‑functional teams and top‑10 countries to unlock patient access to Amgen medicines.

What We Expect Of You

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• Degree in a relevant field with formal or on‑the‑job training in health economics.
• Strong experience in economic modeling and indirect treatment comparisons.
• Proven ability to develop payer-relevant evidence, including RWE, and author protocols and publications.
• Experience designing PRO/COA strategies.
• Expertise in evidence synthesis, including SLRs, ITCs, and meta‑analyses.
• Solid strategic and technical understanding of HTA requirements.
• Experience developing GVDs, AMCP dossiers, economic models, and predictive analytics.
• Demonstrated ability to influence Access strategy through HEOR insights.
• U.S. market and oncology experience is a plus.

What You Can Expect Of Us

• Vast opportunities to learn and move up and across our global organization
Diverse and inclusive community where teammates are empowered to bring ideas to the table and act
• Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits

Location

.tasks Flexibly from home with regular office work either आक from our Cambridge or Uxbridge next‑generation workspace.

Application due date: 23rd January 2026

Apply Now

for a career that defies imagination

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.

Equal Opportunity Statement

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will ensure that individuals with disabilities are provided होते reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.

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