Post-doctoral Research Fellow Level 1

Biostars; Ireland; On-site; EUR 44,000 - 52,000; Full time

Job summary

A leading research institution in Ireland is looking for a Post-doctoral Research Fellow Level 1 to join the Chromatin Architecture in Cancer laboratory. This role involves investigating super-enhancer networks in acute myeloid leukemia and requires a recent PhD graduate or early career researcher. The successful candidate will contribute to understanding complex molecular pathways in cancer treatment. The position offers a competitive salary between €44,847 and €51,313 based on qualifications.

Qualifications

• Candidates must have completed a PhD or have equivalent research experience.
• Early stage researchers who have not exceeded 4 years of total postdoctoral experience.
• Prior experience in pharmacology or related fields is beneficial.

Responsibilities

• Work on targeting the super-enhancer network in acute myeloid leukemia.
• Develop a molecular understanding of patient-specific transcriptional circuits.
• Explore epigenomic pathways in genetically diverse clones.

Education

PhD or equivalent

Job description

Job:Post-doctoral Research Fellow Level 1

Applications are invited for a temporary post of a Post-doctoral Research Fellow Level 1 within UCD School of Biomolecular and Biomedical Science.

The Chromatin Architecture in Cancer laboratory (https://conwaychromatinlab.com/ ) at University College Dublin, led by Dr. Eric Conway, are recruiting a postdoctoral fellow to work on targeting the super-enhancer network in acute myeloid leukemia. This position will be funded through a Wellcome Trust award.Project descriptionAcute myeloid leukemia (AML) has one of the worst prognoses of haematological cancers. It frequently results in post-treatment relapse due to its complex clonal heterogeneity allowing for the expansion of minimal residual disease populations. Therefore, targeting epigenomic pathways common across genetically diverse clones, rather than the dominant clonal genotype, is an avenue that demands exploration. Transcription factor (TF) pathways are imminently druggable due to an expanding library of epigenetic inhibitor compounds, however in order to effectively implement this approach, there must first be a molecular understanding of patient-specific transcriptional circuits.Salary Range: Euro 44,847 - Euro 51,313 per annumAppointment on the above range will be dependent upon qualifications and experience.Closing date: 12:00 noon (local Irish time) on 30th of April 2025.Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 12:00 noon (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.UCD do not require assistance from Recruitment Agencies. Any CV's submitted by Recruitment Agencies will be returned.The PD1 position is intended for early stage researchers, either just after completion of a PhD or for someone entering a new area for the first time. If you have already completed your PD1 stage in UCD or will soon complete a PD1, or you are an external applicant whose total Postdoctoral experience, inclusive of the duration of the advertised post, would exceed 4 years, you should not apply and should refer to PD2 posts instead.Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/

Applications are invited for a temporary post of a Post-doctoral Research Fellow Level 1 within UCD School of Biomolecular and Biomedical Science.

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